Breast cancer is the most prevalent type of invasive cancer attacking women in the United States. Last year alone some 213,000 women were diagnosed with the disease. The good news is that two million women have survived. Many women with breast cancer seek complementary interventions that will enhance their quality of life. Yet research is lacking whether these programs such as yoga, also benefit immune function.
Breast cancer is the most prevalent type of invasive cancer attacking women in the United States. Last year alone some 213,000 women were diagnosed with the disease. The good news is that two million women have survived. Many women with breast cancer seek complementary interventions that will enhance their quality of life. Yet research is lacking whether these programs such as yoga, also benefit immune function.
A new study of breast cancer survivors practicing Iyengar yoga – a form of yoga that incorporates all of the components of physical fitness and focuses on structural alignment of the body as well as mental relaxation – has found that breast cancer survivors who practice yoga have changes in the way their immune cells respond to activation signals, which may be important for understanding how physical activity and meditative practices benefit the immune system. The function of genes in immune cells can be regulated by proteins called transcription factors. Transcription factor nuclear factor-kappa B (NF-? B) is linked to immune cell activation and to the stress response.
Active practice of Iyengar yoga, named for its creator B.K.S. Iyengar, differs from the gentle restorative practices typically offered to cancer survivors as it can include all the components of physical fitness. The active practice of âsanas (postures) can incorporate cardiovascular endurance, muscular strength and endurance, flexibility and balance.
Nineteen women, average age 61 years, diagnosed with stage I-III breast cancer and receiving ant estrogen or aromatize inhibitor hormonal therapy participated in the study. Time since diagnosis was approximately four years. None had any experience with Iyengar yoga. The subjects were randomized to either yoga (n=10) or a wait-list control group (n=9).
Beginning level Iyengar yoga classes were conducted two times per week for eight weeks and included the following yoga poses: standing poses, chest and shoulder openers; and inversions. The women were given a home instruction sheet to practice once a week at home a week at home for a total of three yoga sessions per week.
A survey of the subjects demands of illness and a blood sample to determine lymphocyte NF-?B activation were collected prior to and following the intervention.
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